Business Wire25d
Savara Announces the Rare Lung Disease, Autoimmune Pulmonary Alveolar Proteinosis (aPAP), is Highlighted on a New Episode of “The Balancing Act ® ” Airing on Lifetime ® TV
In a healthy lung, excess surfactant is cleared and digested by immune cells called alveolar macrophages. Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating ...
Medscape1mon
Mechanisms of Acute Respiratory Distress Syndrome in Children and Adults
The pathophysiology of acute respiratory distress syndrome is divided into eight categories: alveolar fluid transport, surfactant, innate immunity, apoptosis, coagulation, direct alveolar ...
Business Wire1mon
Savara Announces Expanded Access Program (EAP) for Molgramostim Inhalation Solution (Molgramostim) for Patients with Autoimmune Pulmonary Alveolar Proteinosis (aPAP)
In a healthy lung, excess surfactant is cleared and digested by immune cells called alveolar macrophages. Alveolar macrophages need to be stimulated by granulocyte-macrophage colony-stimulating ...
FiercePharma25d
Savara sponsors Lifetime talk show episode about rare respiratory disease ahead of FDA submission
Pulmonary alveolar proteinosis is caused by a buildup in the lungs’ alveoli of a substance called surfactant that’s made up of proteins and lipids. The buildup can block air from moving ...
Nature1mon
The Rho Pathway Mediates Transition to an Alveolar Type I Cell Phenotype During Static Stretch of Alveolar Type II Cells
The alveolar epithelium is composed of two cell types: type II and type I cells (1). Type II cells are responsible for surfactant production and play a role in lung host defense. Type I cells ...
Nature1mon
Developmental Cell/Molecular Biologic Approach to the Etiology and Treatment of Bronchopulmonary Dysplasia
and the retrograde stimulation of alveolar type II cell surfactant phospholipid and protein synthesis by leptin. Each of these paracrine interactions requires cell-specific receptors on adjacent ...
Medscape1mon
Mechanisms of Acute Respiratory Distress Syndrome in Children and Adults
Future studies of the effect of exogenous surfactant in children and adults ... the determination of differences between the degree of alveolar epithelial injury, inflammatory and innate immune ...