Giant pterosaurs may be the closest real animals to the dragons of Westeros. So if they could fly, surely Dany's dragons could too, right? Well… not exactly. Let's consider the mechanics of flight.
Dungeons & Dragons is filled with several different species with unique abilities. You have your Dragonborns, able to breathe ...
So these dragons would either have bones that are too heavy for takeoff or bones that are too fragile to fly. Either way, they're not going anywhere. That being said, all is not lost for our fire ...