This leads to ribosome production arrest and a potentially alternative way p14 ARF elicits its tumor suppressor function.

Ribosomal RNA also performs the most crucial and ancient function inside ribosomes: the fascinatingly efficient translation of mRNA into protein. The very first proteins must have been made by ...

November 11, 2024) There are processes in the human body that can suppress the growth and proliferation of cancer cells.

which support basic ribosomal functions, and interacts with the Gcn2 kinase, linking the ribosomes to the ISR pathway. We show that P-stalk proteins, which form a pentamer, exist in the cell ...

We identified novel variants in ribosomal protein S6 kinase beta-1 (RPS6KB1 or S6K1 ... the rpS6 and ERK1/2 signalling cascades, suggesting a gain-of-function effect. Contributors PSD conceived, ...

Depletion of eIF3e and partially eIF3d also increased translation of TOP mRNAs that encode mainly ribosomal proteins and other components of ... empirical cumulative distribution functions (ECDFs) of ...

An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this ...

Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A ...

Trying to get in more protein at breakfast? Eggs are a great start. It's pretty typical to use two eggs as the basis for breakfast, whether you're serving them scrambled, hard-boiled or over easy.