Eli Lilly and Company (NYSE: LLY) today announced positive Phase 2 results for muvalaplin, an investigational once-daily, orally administered selective inhibitor of lipoprotein(a) [Lp(a)], a ...

The placebo-adjusted reductions were up to 85.8% using an intact Lp(a) assay and up to 70.0% using an apo(a) assay. Specifically, the reductions were 47.6% at 10 mg, 81.7% at 60 mg and 85.8% at 240 mg ...

One is an siRNA biologic, the other an oral agent, but both lowered Lp(a) levels by 80% or more in ASCVD patients.

Muvalaplin works, Nicholls explained at the press briefing, by disrupting the bonding of apo(a) to apoB, which does not allow Lp(a) to form. The study examined 3 different doses, at 10 mg, 60 mg, and ...

(30) First, TOPO (3.00 g, 7.76 mmol), ODPA (280 mg, 0.837 mmol), and CdO (60.1 mg ... The crude product was purified by diluting with toluene (5 mL), precipitating with methanol (10 mL), centrifuging ...

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Investors with a lot of money to spend have taken a bullish stance on Apollo Global Management APO. And retail traders should know. We noticed this today when the trades showed up on publicly ...

This would suggest that the previously reported inverse relationships of HDL-C and apo A-I with CAD do not hold ... However, at very high levels of HDL-C (≥70 mg/dL), this inverse relationship ...

Get detailed information on Clobazam, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it. The updated prescription ...