The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that ...

Their new discovery is detailed in the paper titled "Design of novel and highly selective SARS-CoV-2 main protease inhibitors ...

Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the ...

Food indeed contributes to the pharmacokinetic variability of protease inhibitors (PIs). [1] The exact mechanism(s) are poorly understood. As determined by measuring the area under the ...

The MMPs were the first protease targets seriously considered for combating cancer because of their role in extracellular matrix degradation. Several MMP inhibitors, which can be generally divided ...

Nucleoside reverse transcriptase inhibitor; PI: Protease inhibitor; PK: Pharmacokinetics; RPV: Rilpivirine. Data taken from [10,33–38]. Blake Max's spouse is employed as a regional medical ...

BOTHELL, Wash., Nov. 13, 2024 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (Nasdaq: COCP) (“Cocrystal” or the “Company”) reports financial results for the three and nine months ended September 30, 2024, ...

Australia: A recent study published in Clinical Infectious Diseases has shown that the current use of integrase strand ...

COVID: Phase 1 pharmacokinetic profile supports the potential for ratutrelvir to be dosed as a once-a-day, single drug, 10-day treatment course, ...